IV & NAD+ Therapy
IV and NAD+ Therapy in Columbia, MD: What to Know Before Your First Session
IV therapy delivers fluids, vitamins, and nutrients directly into the bloodstream, and NAD+ infusions are a specific type. Here is what the evidence shows and what to expect.
Reviewed by the clinical team at Zest Regen Health · October 9, 2026 · 7 min read
Content managed by Phil Kim, Lucky Consulting Group
IV therapy delivers fluids, vitamins, and other nutrients directly into the bloodstream, and NAD+ infusions are a specific type of IV therapy aimed at cellular energy and recovery. At Zest Regen Health in Columbia, Maryland, IV and NAD+ sessions are offered after an evaluation, with honest expectations: the evidence for many wellness infusions is limited, and they are best viewed as one part of a broader plan rather than a quick fix.
What IV therapy is used for
- Hydration and nutrient support
- Recovery after illness, travel, or heavy exertion
- Vitamin and nutrient supplementation under clinical guidance
- NAD+ infusions for energy and recovery goals
IV therapy is not a treatment for medical conditions without evaluation, and it does not replace medical care for an underlying problem.
What the evidence shows about IV vitamins
High-quality evidence for IV vitamin therapy in healthy people is limited. Oral nutrition is well studied, and the IV route bypasses digestion, but studies have not consistently shown that IV vitamin infusions outperform oral supplementation for wellness outcomes. This is why the responsible approach is to review what you actually need before scheduling an infusion.
What the evidence shows about NAD+
No rigorous outcomes trial has shown that IV NAD+ improves energy, fatigue, or aging in healthy adults. A 2026 narrative review in Frontiers in Aging concluded that current evidence is preliminary and insufficient to support routine clinical or wellness use, and small studies have reported side effects including nausea, abdominal cramping, and chest pressure during infusions. The FDA has also issued recalls and warnings around compounded NAD+ products, so sourcing and preparation standards matter.
What a session at the Columbia clinic looks like
- Evaluation first: your history, medications, and goals are reviewed before any infusion.
- The IV is placed and the infusion is started at an appropriate rate.
- NAD+ infusions are typically slow, often two to four hours, with the care team monitoring you.
- After the session, you receive guidance on hydration, activity, and whether follow-up sessions may be appropriate.
Who may consider IV or NAD+ therapy
- People with specific recovery or wellness goals who have completed an evaluation
- People who understand the current evidence and set realistic expectations
- People without contraindications identified during the evaluation
See IV therapy at the Columbia clinic (/services/iv-therapy/).
Explore NAD+ therapy (/services/nad-therapy/).
Read the basics: what is IV therapy (/blog/what-is-iv-therapy/).
Meet the physicians who evaluate patients at Zest (/dr-francisco-ward/).
Sources & further reading
- Narrative review of intravenous NAD+ and NAD+ precursors in wellness and translational medicine (Frontiers in Aging, 2026)
- Evaluation of safety and effectiveness of NAD in different clinical conditions: a systematic review (2024)
- Intravenous NAD+ versus nicotinamide riboside: a retrospective tolerability pilot study (2026)
- FDA: FDA Reminds Compounders to Use Ingredients Suitable for Sterile Compounding (October 2024)
Next step
If you are considering IV or NAD+ therapy, start with a conversation about whether it fits your goals. Book a free 15-minute consultation at the Columbia clinic to discuss your history and what an infusion program would and would not do for you.
Talk with our care team about this topic
A member of our clinical team can answer your questions at the Columbia, Maryland clinic. If IV Therapy may be appropriate for you, the first step is a consultation.
Care at Zest Regen Health is physician-guided. Meet our physicians, who evaluate patients at the Columbia, Maryland clinic.